By Richard W. Light MD
Now in a completely revised and up to date 6th variation, Dr. Light's vintage textual content, Pleural illnesses, gives you much more targeted content material at the pathophysiology, scientific manifestations, analysis, and administration of pleural illnesses. The text’s uncomplicated, single-author point of view combines procedural services, insights on contemporary technical advances, and transparent techniques for either prognosis and treatment.
This version contains present and well timed details on administration of either paraneoplastic and malignant pleural effusions, new cautions concerning the want for education in thoracentesis, prognosis of tuberculous pleural effusions, and more recent brokers for generating effusions.
Inside this robust, fact-packed resource…
• 3 algorithms for analysis of pleural effusions aid establish reasons of pathologic findings.
• Chapters on thoracentesis, pleural biopsy, chest tube insertion, and thoracoscopy supply symptoms and contraindications besides step by step procedural guidance.
• distinct insurance of parapneumonic and malignant pleural effusions addresses the latest advances in treatment.
NEW to the 6th Edition…
• up-to-date remedy regimens for paraneoplastic lesions increase healing options.
• Consensus-building content material provides a unified method of using indwelling catheters within the administration of malignant pleural effusions.
• New emphasis on education for thoracentesis is helping reduce procedure-related morbidity and mortality.
• New concepts relating to chest tubes aid make sure the right tube is used for every procedure.
• New assessments refine the prognosis of tuberculous pleural effusions.
PLUS… a unfastened spouse site presents on-demand entry to the absolutely searchable textual content and photographs.
Read Online or Download Pleural Diseases PDF
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Extra info for Pleural Diseases
Sample text
Chest. 1 999; 1 1 5 : 1 066- 1 069. 55. Allen SJ, Laine GA, Drake RE, et al. Superior vena caval pres sure elevation causes pleural effusion formation in sheep. Am J Physiol. 1 988;255:H492-H49 5 . 56. Verkman AS, Matthay MA, Song Y. Aquaporin water chan nels and lung physiology. Am J Physiol Lung Cell Mo! Physiol. 2000;278:L867-L879. 57. Borok Z, Verkman AS . Lung edema clearance: 20 years of progress: invited review: role of aquaporin water chan nels in fluid transport in lung and airways.
VEGF receptors have been dem onstrated on mesothelial cells (53), and the levels of VEGF are higher in exudative effusions than in tran sudative pleural effusions (52,53). Of course, if the pleural surfaces become inflamed, the permeability of the capillaries may be increased. Increased Interstitial Fluid Decreased Oncotic Pressure Gradient The most common cause of increased pleural fluid formation is increased interstitial fluid in the lung. As mentioned earlier, whenever the amount of edema in the lung exceeds 5 g/gram of dry lung weight, pleural fluid accumulates, irrespective of whether the edema is due to high-protein or low-protein fluid (24) .
The most common situation producing a decrease in the pleural pressure is bronchial obstruction leading to atelectasis of the lower lobe or complete lung. A decrease in the pleural pressure also occurs when the visceral pleura becomes coated with a collagenous peel and the lung becomes trapped. In these in stances, the pleural pressure can become very negative (below - 50 cm H p ) (5 1 ) . Decreased pleural pres sures can also contribute to pleural fluid accumula tion in diseases in which the elastic recoil of the lung is increased.
