By Syracuse Research Corporation
The ATSDR toxicological profile succinctly signify the toxicological and opposed healthiness results details for the unsafe substance defined therein. the point of interest of the profiles is on health and wellbeing toxicological details; accordingly each one toxicological profile starts off with a public future health assertion that describes, in nontechnical language, a substance's suitable toxicological houses.
Read Online or Download Toxicological profiles - Vinyl Chloride PDF
Similar pharmacology books
Enzyme Technologies for Pharmaceutical and Biotechnological Applications
Eli Lily and corporate, Greenfield, identity. Reference offering an up to date evaluation of enzyme services in human and animal healthiness, together with insurance of recent and rising applied sciences in biotechnical and pharmaceutical industries. Emphasizes sleek tools of metabolic engineering and drug discovery techniques, and info enzymes concerning human sickness.
Clinician's Pocket Drug Reference 2009
Must-know information regarding a thousand of the main everyday medictions -- at your fingertips and able to use! compliment for a prior version: "This is a truly invaluable and up to date pocket reference for general medicinal drugs. five Stars! "--Doody's evaluation carrier Why spend time plowing via info you do not need while what you really want to understand is correct the following in a single concise consultant?
Warfarin - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
This can be a 3-in-1 reference booklet. It provides an entire scientific dictionary protecting hundreds of thousands of phrases and expressions in terms of warfarin. It additionally provides wide lists of bibliographic citations. eventually, it offers details to clients on how one can replace their wisdom utilizing numerous web assets.
- Mass Spectrometry
- Quality of Life: Assessment, Analysis and Interpretation
- Pharmacological Assays of Plant-Based Natural Products (Progress in Drug Research, Volume 71)
- Sex Drugs & Mum In The Front Row
- Toxicological profiles - Silver
- Pharmacology of Cholinergic and Adrenergic Transmission. Proceedings of the Second International Pharmacological Meeting, August 20–23, 1963
Extra resources for Toxicological profiles - Vinyl Chloride
Example text
Chronic exposure of rats to 5,000 ppm vinyl chloride 7 hours per day, 5 days per week, for 1 year resulted in increases in areas of myodegeneration in the heart and thickening of the walls of arteries (Feron and Kroes 1979). However, the statistical significance of this effect was not reported. Exposure of rats to 30,000 ppm of vinyl chloride for 4 hours per day, 5 days per week, for 1 year also produced thickening of the walls of small arterial vessels. The thickening was characterized by a proliferation of the endothelium.
1984). Brief exposure of animals to extremely high concentrations of vinyl chloride has been shown to cause hepatic damage. For example, acute exposure (30 minutes) of guinea pigs and mice to 300,000 ppm of vinyl chloride caused liver congestion or severe fatty degeneration while 200,000 ppm caused fatty infiltration in rats (Mastromatteo et al. 1960). -ketoglutarate transaminase activity in rats (Jaeger et al. 1974). However, exposure of rats to 50,000 ppm for 6 hours produced no observable effects on the liver (Reynolds et al.
1983 5 F (CEL: mammary gland carcinoma) Maltoni et al. 1981 TABLE 2-1. Levels of Significant Exposure to Vinyl Chloride - Inhalation (continued) LOAEL (effect) a Key to figure a Species/ (strain) Exposure duration/ frequency 70 Mouse (CD-1) 1-12 mo 5d/wk 6hr/d 71 Hamster (Golden Syrian) 12, 18, 24 mo 5d/wk 6hr/d System NOAEL (ppm) Less serious (ppm) Serious (ppm) 50 B (CEL: hepatic hemangiosarcoma; bronchiolo-alveolar adenoma; malignant lymphoma) 50 F (CEL: mammary gland adenoma and adenocarcinoma) 200 F (CEL: liver hemangiosarcoma; skin carcinoma, hemangiosarcoma; spleen hemangiosarcoma; mammary gland carcinoma; stomach adenoma) Reference Lee et al.
