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Neural Mechanisms of Cardiovascular Regulation by Mark W. Chapleau, Francois M. Abboud (auth.), Nae J. Dun

By Mark W. Chapleau, Francois M. Abboud (auth.), Nae J. Dun Ph.D., Benedito H. Machado Ph.D., Paul M. Pilowsky B.M.B.S., Ph.D. (eds.)

Neural Mechanisms of Cardiovascular Regulation responds to present questions about how neurons within the crucial and peripheral anxious platforms control the cardiovascular process. It encompasses a sequence of considerate studies which are meant to impress and light up the reader, with the goal of unveiling a few of the rules that present practitioners within the box of cardiovascular learn are utilizing to generate their present studies.

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1. , 1990. Carotid sinus baroreceptor sensitivity in experimental heart failure . Circ . 81, 1959-1966. , 1992. Aldosterone reduces baroreceptor discharge in the dog . Hypertension 19,270-277. , 1996. Cardiac sympathetic afferent reflex in dogs with congestive heart failure . Am. 1. Physiol. Regulatory Integr . Comp oPhysiol. 271, R751-R756. , 1994. Chronic administration of aldosterone depresses baroreceptor reflex function in the dog . Hypertension 24, 571-575 . , 1995. Prevention of the excitatory actions of bradykinin by inhibition of PGI 2 formation in nodose neurones of the guinea-pig.

1993) and Zhang and Mifflin (1993), performed under anesthesia, showed that the pressor response was blocked using excitatory amino acid (EAA) receptor antagonists. As it will be emphasized in this chapter, the pressor response in the absence of anesthesia was not blocked by different antagonists of EAA receptors microinjected 34 Chapter 2 into different sub-regions of the NTS, indicating that a direct influence of the anesthetics may alter the processing of this reflex. NEURAL PATHWAYS OF THE CHEMOREFLEX IN THE BRAINSTEM Is the NTS really the first synaptic station of the chemoreflex afferents in the central nervous system?

Circ. Res. 82,416-423. , 1993. Electrophysiological properties and chemosensitivity of guinea pig nodose neurons in vitro. J. Auton. Nerv. Syst. 44, 17-34. , 1990. An experimental and modeling study of the excitability of carotid sinus baroreceptors . Circ. Res. 66, 1510-1525. , 1974. Interaction between adrenergic and cholinergic system: presynaptic inhibitory effect of noradrenaline on acetylcholine release. 1. Neural Trans. Suppl. II , 6178. , 1999. Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.

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