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Intracranial Hypertension (Neurology- Laboratory and by Stefan Mircea Iencean

By Stefan Mircea Iencean

Intracranial high blood pressure (ICH) is the most typical reason for scientific deterioration and demise for neurological and neurosurgical sufferers. there are numerous reasons of raised intracranial strain (ICP) and elevated ICP can produce intracranial high blood pressure syndromes. tracking of intracranial strain and advances in investigations of the principal anxious process have ended in new recommendations and systemisations in intracranial high blood pressure. The descriptive type of the intracranial high blood pressure has been changed by means of an etio-pathogenic type with 4 major teams. Parenchymatous Intracranial high blood pressure, within the extending intracranial procedures (cerebral tumours, intracranial haematoma, cerebral abscesses, etc.), in nerve-racking mind edema, in hypotoxic mind edema, often intoxications with neurotoxins (endogenous or exogenous), and so forth. Vascular Intracranial high blood pressure is as a result of the issues of cerebral blood circulate after which the mind edema or / and mind swelling seems. The vascular intracranial high blood pressure happens in: vascular cerebral illnesses - cerebral venous thrombosis or in cerebral ischaemic stroke and in - extracerebral vascular illnesses as hypertensive encephalopathies. Intracranial high blood pressure is brought on by the problems of the CSF dynamics ( hydrocephalus etc). Idiopathic Intracranial high blood pressure. The therapy of intracranial high blood pressure depends upon the kind of intracranial high blood pressure and at the degree of the disease.

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Extra resources for Intracranial Hypertension (Neurology- Laboratory and Clinical Research Developments)

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5. Brain Blood Barrier The brain blood barrier (BBB) represents the morpho-functional system with a protecting role, which separates the nervous parenchyma from the blood circulation, in order to secure and control the cerebral homeostasis. It is both an anatomic barrier and a system of physicalchemical and biochemical mechanisms of membrane transport, representing a dynamic interface that regulates the exchanges between the blood circulation and the fluids of the nervous system (the parenchymatous interstitial fluid and the cerebrospinal fluid).

The sector of the cerebrospinal fluid, which includes the ventricular system and the sub- arachnoid space. The circulation of the cerebrospinal fluid is also permanently, and it includes a. the fluid circulation through the pre-formed anatomic spaces, from production to resorption b. the mutual transfer circuit with the interstitial fluid the parenchymatous sector, which includes the neurons and the glial cells, mainly the astrocytes and the oligodendrocytes. The nervous parenchyma includes the interstitial fluid in the intercellular space and the cerebrospinal fluid in the ventricular cavities, and it is included in the cerebrospinal fluid existing in the subarachnoid space.

The intracranial arterial vascularization is secured by the internal carotid arteries in a bilateral anterior position, and by the two vertebral arteries in a posterior position. The great cerebral vessels penetrate the subarachnoid space, they form the Willis polygon at the skull base in the inter-peduncular cistern, and then they ramify and enter the nervous parenchyma. The blood vessels are surrounded by Virchow-Robin perivascular spaces here, until they turn into capillaries. The cerebral capillaries continue by venules, surrounded by the perivenular spaces, and then they turn into big veins that flow into the venous sinuses of dura mater.

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