By Toshio Ohshima (auth.), Li-Huei Tsai, Nancy Y. Ip (eds.)
Cyclin established Kinase 5 presents a accomplished and up to date choice of reports at the discovery, signaling mechanisms and features of Cdk5, in addition to the aptitude implication of Cdk5 within the remedy of neurodegenerative illnesses. because the identity of this targeted member of the Cdk relatives, Cdk5 has emerged as some of the most very important sign transduction mediators within the improvement, upkeep and fine-tuning of neuronal services and networking. additional reports have published that Cdk5 is additionally linked to the rules of neuronal survival in the course of improvement in addition to in neurodegenerative ailments. those observations point out that certain keep an eye on of Cdk5 is vital for the rules of neuronal survival. The pivotal function that Cdk5 appears to be like to play in either the legislation of neuronal survival and synaptic services therefore increases the attention-grabbing danger that Cdk5 inhibitors can have healing power for the therapy of a couple of neurodegenerative diseases.
Read Online or Download Cyclin Dependent Kinase 5 (Cdk5) PDF
Similar nonfiction_4 books
Includes papers which specialize in which means, studied not just in monolingual environments, but in addition contrastively in multilingual contexts.
Богато иллюстрированное издание, посвященное немецкому пистолету Savage version 1907. История создания, модификации, клейма, схемы, фото, рисунки.
Фирменный каталог на винтовки Mauser моделей M03 ит M98 за 2007 год.
- The Commons: Its Tragedies and Other Follies (Philosophical Reflections on a Free Society)
- Psalms of Solomon: A Critical Edition of the Greek Text (Jewish and Christian Texts in Contexts and Related Studies)
- Horticultural pests: detection and control
- Foreign Accent: The Ontogeny and Phylogeny of Second Language Phonology (Reflective Teaching and the Social Conditions of Schooling)
Extra resources for Cyclin Dependent Kinase 5 (Cdk5)
Goshima Y, Kawakami T, Hori H, Sugiyama Y, Takasawa S, Hashimoto Y, KagoshimaMaezono M, Takenaka T, Misu Y, Strittmatter SM (1997) A novel action of collapsin: collapsin-1 increases antero- and retrograde axoplasmic transport independently of growth cone collapse. J Neurobiol 33:316–328. Goshima Y, Hori H, Sasaki Y, Yang T, Kagoshima-Maezono M, Li C, Takenaka T, Nakamura F, Takahashi T, Strittmatter SM, Misu Y, Kawakami T (1999) Growth cone neuropilin-1 mediates collapsin-1/Sema III facilitation of antero- and retrograde axoplasmic transport.
Nat Neurosci 7:1222–1232. Meriane M, Tcherkezian J, Webber CA, Danek EI, Triki I, McFarlane S, Bloch-Gallego E, Lamarche-Vane N (2004) Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance. J Cell Biol 167:687–698. Morita A, Yamashita N, Sasaki Y, Uchida Y, Nakajima O, Nakamura F, Yagi T, Taniguchi M, Usui H, Katoh-Semba R, Takei K, Goshima Y (2006) Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling. J Neurosci 26:2971–2980. Morse WR, Whitesides III JG, LaMantia AS, Maness PF (1998) p59fyn and pp60c-src modulate axonal guidance in the developing mouse olfactory pathway.
272, 13419–13425. , and Benfenati, F. (1993). Synaptic vesicle phosphoproteins and regulation of synaptic function. Science 259, 780–785. C. (1993b). Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin. Nature 366, 347–351. C. (1993a). Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin. Nature 366, 347–351. , and Yazaki, K. (1994). Phosphorylation of dynamin by cdc2 kinase. Biochem. Biophys. Res. Commun. 202, 1127–1133. B. and Greengard, P. (1979).