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Atlas of Clinical Sleep Medicine: Expert consult - Online by Meir H. Kryger MD

By Meir H. Kryger MD

From Meir H. Kryger, MD, the editor of the definitive source in sleep, ideas and perform of Sleep drugs, comes the Atlas of scientific Sleep drugs. This hugely illustrated atlas will give you a superb visible relief to the main complete, authoritative, and up to date info for diagnosing and treating grownup and pediatric sufferers with sleep problems. it's the first atlas that makes use of the hot scoring ideas, and studies find out how to use the recent AASM scoring guide that is helping you ranking, interpret, and diagnose sleep issues. every one bankruptcy info the physiologic, scientific, morphologic, and investigational elements of the entire variety of sleep problems you come upon in daily perform. medical details is gifted in an easy-to-understand variety, and the combination of colour deals elevated visible tips. Plus, with professional seek advice performance, you will have easy accessibility to the total textual content on-line, in addition to the entire book's illustrations, greater than 20 movies of sufferer interviews, over forty sleep lab movies, and two hundred plus polysomnogram fragments at

  • Includes entry to the full-text on-line at, in addition to the entire book's illustrations, greater than 20 movies of sufferer interviews, together with narcolepsy and stressed leg syndrome, over forty sleep lab video clips, together with obstructive sleep apnea and respiration illnesses, and two hundred plus polysomnogram fragments.
  • Uses the hot scoring ideas, and studies tips to use the recent AASM scoring handbook that is helping you rating, interpret, and diagnose sleep disorders.
  • Covers the whole variety of sleep problems so that you can diagnose any you notice.
  • Features discussions of pediatric stipulations resembling pediatric congenital illnesses so that you can larger diagnose and deal with this specified staff.
  • Contains a wealth of top quality polysomnograms taken from the newest machines utilized by associations round the world.
  • Emphasizes pharmacology and comprises information regarding the most recent medicines on hand in addition to these in medical trials that will help you be sure the simplest and newest drug therapy.
  • Uses photos and drawings to successfully describe the body structure of sleep drugs to assist make tough options more straightforward to understand.
  • Offers a full-color compendium that mixes the body structure of sleep with the correct findings to offer an entire photo of the way sleep impacts every one physique system.
  • Uses a constant, easy-to-follow bankruptcy structure that makes reference easy.

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Additional resources for Atlas of Clinical Sleep Medicine: Expert consult - Online and Print, 1e

Example text

Orexin Sleep VLPOc VLPOex Homeostatic sleep drive Circadian ‘Hypnotic’ signal TMN LC-Raphe Awake Orexin TMN LC-Raphe VLPOc VLPOex Circadian ‘Alerting’ signal The ventrolateral preoptic (VLPO) area contains two populations of neurons. The first is a cluster of neurons in the “core” of the VLPO (VLPOc) that projects most heavily to the tuberomammillary nucleus (TMN). , extended VLPO; VLPOex) and projects more heavily to the locus coeruleus (LC) and the dorsal and median raphe nuclei. This interaction between the VLPOex and components of the arousal system is mutually inhibitory and as such these pathways function analogously to an electronic “flipflop” switch/circuit.

4-11. Overview of functional changes during sleep. 05 ЊC 34 Chapter 3 / THE BIOLOGY OF SLEEP: CYTOKINES, HOST DEFENSE, AND SLEEP Acknowledgments The author is grateful to Dr. Roberto Amici and Dr. Meir Kryger for useful suggestions and technical help. SELECTED READINGS Azzaroni A, Parmeggiani PL: Mechanisms underlying hypothalamic temperature changes during sleep in mammals. Brain Res 632:136–142, 1993. Calasso M, Parmeggiani PL: Carotid blood flow during REMS. Sleep 31:701–707, 2008. Dewasmes G, Bothorel B, Candas V, Libert JP: A short-term poikilothermic period occurs just after paradoxical sleep onset in humans: Characterization changes in sweating effector activity.

By contrast, lesions of the basal forebrain and anterior hypothalamus (horizontal hatching) produced profound insomnia. Von Economo also observed that lesions between these two sites (arrow), which included the lateral hypothalamic area, caused narcolepsy. (From Von Economo C: Sleep as a problem of localization. 1-2. See opposite page for legend Bulb Atlas of Clinical Sleep Medicine Thalamus Thalamus LH (ORX. 1-3. A, In the 1970s and 1980s, the neurochemistry of several brainstem “arousal” centers was elaborated.

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