By Malo, Jean-Luc
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Additional resources for Asthma in the Workplace, Fourth Edition
An effect estimate for a specific or all occupational exposures, in the form of incidence rate ratio (IRR); 2. an estimate of AF calculated based on this; and 3. an estimate of PAF calculated based on AF and the prevalence of occupational exposure(s) of interest in the population for which the assessment is made (Pe). Incident rate ratio gives an estimate of the risk of developing asthma in relation to the exposure of interest and can be calculated according to a methodology detailed thoroughly in another publication (5).
It is important to have trained technicians to calibrate the equipment and deal with potential problems. The technicians should also be trained to recognize poor subject performance (60). Poor performance, in particular, poor reproducibility, may also be a marker of airway dysfunction (61). Several factors need to be considered in choosing the lung function tests: the cost of equipment, the testing time, the simplicity of the test, and analysis of results, reproducibility, acceptability, and the degree of standardization of the instrument and test procedures.
Faster results than for cohort studies. Recall bias with possible overestimation of risk. Exposure and disease not necessarily confirmed in a similar way in cases and controls. “Healthy worker survivor effect” Case-crossover studies Compare the exposure distribution during a hazard period. Cases serve as their own controls. Good for assessing work aggravated asthma Eliminate potential confounding by subject characteristics. Eliminate the concern about potential differences in selection of cases and controls.