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Thin Layer Chromatography in Drug Analysis by Lukasz Komsta, Monika Waksmundzka-Hajnos, Joseph Sherma

By Lukasz Komsta, Monika Waksmundzka-Hajnos, Joseph Sherma

Used generally in drug keep watch over laboratories, forensic laboratories, and as a study device, skinny layer chromatography (TLC) performs an immense function in pharmaceutical drug analyses. It calls for simpler or dear gear than different innovations, and has the power to be played below box stipulations. Filling the necessity for an updated, entire reference, Thin Layer Chromatography in Drug Analysis covers an important equipment in pharmaceutical purposes of TLC, specifically, research of bulk drug fabric and pharmaceutical formulations, degradation stories, research of organic samples, optimization of the separation of drug sessions, and lipophilicity estimation.

The ebook is split into components. half I is dedicated to basic issues regarding TLC within the context of drug research, together with the chemical foundation of TLC, pattern pleparation, the optimization of layers and cellular levels, detection and quantification, research of ionic compounds, and separation and research of chiral elements. The textual content addresses the most recent advances in TLC instrumentation, two-dimensional TLC, quantification by way of slit scanning densitometry and picture research, statistical processing of knowledge, and diverse detection and identity equipment. It additionally describes using TLC for fixing a key factor within the drug market—the presence of substandard and counterfeit pharmaceutical products.

Part II offers an in-depth evaluate of a variety of TLC purposes for separation and research of specific drug teams. every one bankruptcy comprises an creation concerning the buildings and medicinal activities of the defined components and a literature assessment in their TLC research. an invaluable source for chromatographers, pharmacists, analytical chemists, scholars, and R&D, medical, and forensic laboratories, this booklet can be used as a guide, reference, and educating source.

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