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Stereotactic Body Radiation Therapy: Principles and by Yasushi Nagata

By Yasushi Nagata

This ebook serves as a realistic consultant for using stereotactic physique radiation treatment in clinics. at the foundation of greater than 10 years of scientific event with lung melanoma, liver melanoma and different cancers, a extraordinary quantity of information has been accrued. while, nice growth in concepts has been accomplished. a number of new solving apparatuses, new respiration law strategies, new dose fractionation schedules and new image-guided radiation treatment machines were built. This ebook studies the background of these advancements and studies on quite a few different types of toxicities. evaluate of modern scientific reports can be integrated. The authors have been key participants of the JCOG 0403 medical trials on stereotactic physique radiation remedy (SBRT) for either inoperable and operableT1N0M0 fundamental lung melanoma. Readers will research of some of the best results got with SBRT for lung melanoma and different cancers when it comes to neighborhood keep an eye on and toxicities. With its useful concentration, this publication will gain radiation oncologists, scientific physicists, scientific dosimetrists, radiation therapists and senior nurses in addition to scientific oncologists and surgical oncologists who're drawn to radiotherapy.

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Extra info for Stereotactic Body Radiation Therapy: Principles and Practices

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Dose-response in stereotactic irradiation of lung tumors. Radiother Oncol. 2005;77:83–7. 17. Milano MT, Katz AW, Schell MC, et al. Descriptive analysis of oligometastatic lesions treated with curative-intent stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys. 2008;72:1516–22. 18. Onishi H, Shirato H, Nagata Y, et al. Stereotactic body radiotherapy (SBRT) for operable stage I non-small-cell lung cancer: can SBRT be comparable to surgery? Int J Radiat Oncol Biol Phys. 2011;81:1352–8. 19.

Their energy in radiation therapy is expressed in the unit of MeV. The energy of an electromagnetic wave E is expressed by the following equation including Planck’s constant h: E½MeVŠ ¼ h Á ν ¼  à hÁc % 4:14  10À21 Á ν s-1 % 1:24  10À12 =λ½mŠ: λ ð3:2Þ As shown in Fig. 1, when matter is irradiated with an incident charged particle, an electromagnetic wave is released from outside of the nucleus in the form of an X-ray, while one is released by the nucleus in the form of a gamma ray. When the incident charged particle is an electron, bremsstrahlung is produced when the direction of the electron is deflected by the Coulomb force of the nucleus of the matter during its passage through the matter.

1996;34:859–65. 27. Otsuka S, Shibamoto Y, Iwata H, et al. Compatibility of the linear-quadratic formalism and biologically effective dose concept to high-dose-per-fraction irradiation in a murine tumor. Int J Radiat Oncol Biol Phys. 2011;81:1538–43. 28. Douglas BG, Fowler JF. The effect of multiple small doses of x rays on skin reactions in the mouse and a basic interpretation. Radiat Res. 1976;66:401–26. 29. van der Kogel AJ. Chronic effects of neutrons and charged particles on spinal cord, lung, and rectum.

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