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Example text
5 cases/million/year for the period 1953–1968. 7/million/year for the next decade (1973–1982). However, this latter figure of almost 19/million/year was quite similar to the incidence rate reported in Michigan [14] of 21 new cases/million/year for the study period of 1989–1991 suggesting that the increase in incidence did not continue. , utilizing claims data from a large US managed care population, suggested a higher incidence and lower prevalence [8]. This study differed from the earlier Pennsylvania and Michigan-based studies, because it used data from across the USA.
Described in a meta-analysis by Janowsky et al. [75, 76] concluded that there was in fact no association between SSc and breast implants. Solvents Silica As noted above, numerous environmental factors have been associated with SSc in case reports and small case series, but few have been verified in case-control studies. One of the most frequently reported exposures to be associated with SSc is silica. Occupational exposure to particulate silica or silica dust occurs in professions such as mining, sandblasting, and pottery.
Utilizing claims data from a large US managed care population, suggested a higher incidence and lower prevalence [8]. This study differed from the earlier Pennsylvania and Michigan-based studies, because it used data from across the USA. However, since this was based on claims rather than record review, there could be coding errors, and it is possible that the incidence rates are inflated because some could have had SSc prior to the study period. 8 in 1999 (all incidence figures are per million per year).
