By Gokhan Ozyigit, Ugur Selek, Erkan Topkan
This evidence-based advisor at the use of radiotherapy in sufferers with universal malignancies of the lung, esophagus, and thymus might help radiation oncologists to convey optimum care inside a multidisciplinary surroundings. designated info is equipped on all features, from delineation of tumor volumes and organs in danger in line with 4-dimensional CT simulation via to some of the complicated radiotherapy thoughts, together with stereotactic ablative radiotherapy (SABR), intensity-modulated radiation remedy (IMRT), tomotherapy, volumetric modulated arc remedy (VMAT), and proton remedy. Contouring, remedy making plans, and remedy supply are documented in various daily circumstances, with illustrations of slice-by-slice delineations on making plans CT photographs and finalized treatments in keeping with specific popularity standards. a variety of sensible guidance are highlighted, and appropriate details is incorporated on surgical ideas and systemic cures. The publication will facilitate determination making within the administration of sufferers with universal thoracic malignancies and help in overcoming the demanding situations encountered in day-by-day scientific practice.
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Extra resources for Principles and Practice of Radiotherapy Techniques in Thoracic Malignancies
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Liao et al. documented MD Anderson experience on outcome of the clinical use of conventional CT simulated and 3D conformally treated patients in years compared with 4D-CT-simulated and intensity-modulated treated cases, revealing a significant decrease in treatment-related toxicity and improvement in survival with the latter [42]. As more accurate targeting and margin reduction sound to result in significant dose reduction to lung and heart leading to improved quality of life, 4D-CT seemed to be the key component of dose escalation in lung cancer radiotherapy [42].
Okubo M, Nishimura Y, Nakamatsu K, Okumura M, Shibata T, Kanamori S, Hanaoka K, Hosono M. Radiation treatment planning using positron emission and computed tomography for lung and pharyngeal cancers: a multiple-threshold method for [(18)F]fluoro-2deoxyglucose activity. Int J Radiat Oncol Biol Phys. 2010;77(2):350–6. 15. Caldwell CB, Mah K, Skinner M, Danjoux CE. Can PET provide the 3D extent of tumor motion for individualized internal target volumes? A phantom study of the limitations of CT and the promise of PET.
Selek U, Bolukbasi Y, Welsh JW, Topkan E. Intensity-modulated radiotherapy versus 3-dimensional conformal radiotherapy strategies for locally advanced non-small-cell lung cancer. Balkan Med J. 2014;31(4):286–94. 8. Glide-Hurst CK, Chetty IJ. Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies. J Thorac Dis. 2014;6(4):303–18. 9. Zhu A, Marcus DM, Shu HK, Shim H. Application of metabolic PET imaging in radiation oncology. Radiat Res. 2012;177(4):436–48.
