By Gregg L. Semenza, Chandan K. Sen
The power of cells to experience and reply to alterations in oxygenation underlies a large number of developmental, physiological, and pathological strategies. This quantity offers a accomplished compendium of experimental methods to the research of oxygen sensing in forty eight chapters which are written by means of leaders of their fields.
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193, 373 (1978). 4 C. Youngson, C. A. Nurse, H. Yeger, and E. Cutz, Nature 365, 153 (1993). 5 E. Cutz, V. Speirs, H. Yeger, C. Newman, D. Wang, and D. G. Perrin, Anat. Rec. 236, 41 (1993). 6 X. W. Fu, C. A. Nurse, Y. T. Wang, and E. Cutz, J. Physiol. 514, 139 (1999). 7 E. Cutz and A. Jackson, Respir. Physiol. 115, 201 (1999). 8 E. Cutz, X. W. Fu, H. Yeger, C. Peers, and P. J. Kemp, in ‘‘Oxygen Sensing: Responses and Adaptation to Hypoxia’’ (S. Lahiri, G. Semenza, and N. 567. Dekker, New York, 2003.
Methods in enzymology xli Volume 352. Redox Cell Biology and Genetics (Part A) Edited by Chandan K. Sen and Lester Packer Volume 353. Redox Cell Biology and Genetics (Part B) Edited by Chandan K. Sen and Lester Packer Volume 354. Enzyme Kinetics and Mechanisms (Part F: Detection and Characterization of Enzyme Reaction Intermediates) Edited by Daniel L. Purich Volume 355. Cumulative Subject Index Volumes 321–354 Volume 356. Laser Capture Microscopy and Microdissection Edited by P. Michael Conn Volume 357.
M. Hill, V. A. Snetkov, T. P. Robertson, and J. P. Ward, J. Physiol. 536, 211 (2001). 58 G. B. Waypa, N. S. Chandel, and P. T. Schumacker, Circ. Res. 88, 1259 (2001). 59 D. Wang, C. Youngson, V. Wong, H. Yeger, M. C. Dinauer, E. Vega-Saenz de Miera, B. Rudy, and E. Cutz, Proc. Natl. Acad. Sci. USA 93, 13182 (1996). 60 I. O’Kelly, R. H. Stephens, C. Peers, and P. J. Kemp, Am. J. Physiol. 276, L96 (1999). [1] O2 sensing by model cell lines 19 Fig. 5. Acute O2 sensing in H146 cells lacking functional mitochondria (0 cells).
