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Oxford Case Histories in Respiratory Medicine by John Stradling, Andrew Stanton, Annabel H. Nickol, Helen E.

By John Stradling, Andrew Stanton, Annabel H. Nickol, Helen E. Davies, Najib M. Rahman

Dependent round the curriculum for professional trainees in breathing drugs and designed for these getting ready for go out assessments, this ebook includes forty four well-structured, peer-reviewed circumstances accumulated from the Oxford Hospitals, comprehensively protecting a few of the issues of the breathing process. New advancements in scientific education at junior and registrar degrees have created a necessity for a set of circumstances which allow self-assessment, directed at post-graduates. every one case includes a short medical historical past and appropriate exam findings, information of investigations, scientific imaging by means of questions about differential prognosis, and administration and particular solutions and dialogue.

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Further reading Poletti V, Casoni G, Chilosi M, Zompatori M (2006). Diffuse panbronchiolitis. Eur Respir J; 28: 862–871. This page intentionally left blank 30 CASE HISTORIES IN RESPIRATORY MEDICINE Case 5 A 51-year-old lady presented to A&E with shortness of breath for several months, much worse over the last 2 days, now with orthopnoea. Because of associated ankle swelling, she had been treated with diuretics 2 weeks earlier, which produced a 5kg weight loss and some temporary improvement in her shortness of breath.

G. bosentan) are often used in combination. Referral of patients with pulmonary hypertension to a specialist centre should be made. Calcium channel blockers, such as nifedipine, may be used to treat symptoms of Raynaud’s phenomenon, although they do not reverse skin changes, and may worsen oesophageal dysmotility. An alternative option is topical glycerol trinitrate paste. g. inhaled iloprost, oral beraprost and subcutaneous treprostinil, have been shown to have a beneficial effect on the vascular manifestations of systemic sclerosis, including both pulmonary hypertension (associated with significant improvements in various pulmonary function, 6-minute walk test and dyspnoea index) and Raynaud’s phenomenon.

2006). Cyclophosphamide versus placebo in scleroderma lung disease. N Engl J Med; 345: 2655–2666. Supra-normal carbon monoxide transfer factor in restrictive lung disease Hart N, Cramer D, Ward S et al. (2002). Effect of pattern and severity of respiratory muscle weakness on carbon monoxide gas transfer and lung volumes. Eur Respir J; 20: 1–7. 21 Case 4 A 42-year-old Caucasian female was referred with a cough. She had been diagnosed with asthma 6 years previously on the basis of a recurrent cough, productive of clear or purulent sputum, and exertional breathlessness; she had no history of wheeze and her peak flow values did not vary significantly.

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