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Macular and Retinal Diseases: Recent Advances in Diagnosis by Peter Wiedemann, L. Kohen

By Peter Wiedemann, L. Kohen

Provides fresh scientific methods within the prognosis and therapy of macular ailments. The textual content discusses macular gap surgical procedure intimately, in addition to various healing ways for age-related macular degeneration. an outline of advances in laser scanning ophthalmoscopy and in multi-focal ERG is usually incorporated. different papers study problems within the elimination of the posterior vitreous cortex, using intraocular implants for drug supply, and a evaluation of present experimental treatments for AMD.

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Our study with 50 eyes seems to support a high success rate with autologous platelet concentrate. In this study, 74 % of patients had an improvement in visual acuity of 2 lines or more. Most authors have used the two-line criterion as a mea- Minihan/Cleary 40 sure of visual success. In Kelly and Wendel's [2] initial study, 42 % of cases were a visual success. This improved to 55 % in their follow-up study [11]. Glaser's group [3] achieved 85 % visual success using TGF-b2. Fine [13] suggested an arbitrary figure of 6/12 as a target for the successful treatment of macular holes, and it is perhaps actual visual acuity which is more important than lines of improvement.

This fluid was then aspirated. The autologous platelet concentrate was prepared immediately prior to the proce dure in the manner described by Gaudric et al. [7]. 40 ml of venous blood was taken from the patient and gently mixed with 6 ml of acid citrate dextrose (ACD). The mixture was centrifuged at 280 g for 15 min and the platelet rich plasma decanted. This plasma was mixed with 1/8 volume of ACD, and further centrifuged at 1,000 g for 10 min. 6 ml of sodium chloride to achieve a platelet suspension.

Ophthalmology 1994;101:682 686. Advances in the Management of Vitreomacular Traction Syndrome 25 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 Madreperla SA, McCuen BW, Hickingbotham D, Green WR: Clinicopathologic correlation of surgically removed macular hole opercula. Am J Ophthalmol 1995;120:197 207. Yooh HS, Brooks HL, Jr, Capone A, Jr, L'Hernault NL, Grossniklaus HE: Ultrastructural fea tures of tissue removed during idiopathic macular hole surgery. Am J Ophthalmol 1996;122:67 75.

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