By Charles L. Wilkins, Sarah Trimpin
The analytical energy of ion mobility spectrometry-mass spectrometry (IMS-MS) tools is poised to strengthen this know-how from study to analytical laboratories. Exploring those advancements at this serious juncture, Ion Mobility Spectrometry-Mass Spectrometry: conception and Applications covers the instruments, thoughts, and purposes concerned while molecular measurement and form details is mixed with the well known analytical merits of high-performance mass spectrometry.
One of the main interesting advancements in modern Mass Spectrometry
After providing an outline bankruptcy and the basics, the booklet specializes in instrumentation and ionization resources. It describes an ion-mobility-capable quadrupole time-of-flight mass spectrometer, the differential mobility analyzer, a cryogenic-temperature ion mobility mass spectrometer, the atmospheric solids research probe procedure, and laserspray ionization. within the ultimate applications-oriented chapters, the participants discover how homebuilt and advertisement tools utilizing electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) equipment are hired to resolve organic and artificial issues.
Harness the ability of IMS-MS for examining advanced Substances
This paintings is helping readers unexpected with IMS-MS to appreciate its primary thought and useful purposes. It additionally encourages them to enquire the aptitude analytical makes use of of IMS-MS and additional discover the ability of this technique. quite a few colour figures are integrated on a CD-ROM.
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Additional info for Ion mobility spectrometry-mass spectrometry : theory and applications
Example text
Bowers, M. , “A new, higher resolution, ion mobility mass spectrometer”, Int J Mass Spectrom 2009, 287, 46–57. 20. ; Hudgins, R. ; Clemmer, D. ; Jarrold, M. , “High-resolution ion mobility measurements”, Rev Sci Instrum 1997, 68, 1122–1129. 21. , “Paschen curves for helium”, Electra 1977, 52, 82–86. 22. , “Breakdown characteristics of helium and nitrogen at kHz frequency range in partial vacuum for point-to-point electrode configuration”, IEEE T Dielect El In 2008, 15, 749–755. 23. Baker, E. ; Fee, D.
Kolakowski, B. , “Review of applications of high-field asymmetric waveform ion mobility spectrometry (FAIMS) and differential mobility spectrometry (DMS)”, Analyst 2007, 132, 842–864. 27. Pringle, S. ; Wildgoose, J. ; Williams, J. ; Slade, S. ; Bateman, R. ; Bowers, M. ; Scrivens, J. , “An investigation of the mobility separation of some peptide and protein ions using a new hybrid quadrupole/travelling wave IMS/oa-ToF instrument”, Int J Mass Spectrom 2007, 261, 1–12. 28. Shvartsburg, A. ; Smith, R.
49) Hence the intense features in the m/z = 708 ATD are assigned to a singly protonated monomer and doubly protonated dimer with cross sections of 191 and 310 Å2, respectively, and some of the weaker features are likely multiply protonated oligomers. 3 is the “fill-in” between the monomer and dimer peaks. The shape of this ATD is exactly what we expect for a reactive ion A converting into B. 3a. The components are nonreactive species A and B present at the entrance to the drift tube, and reactive species A converting into B inside the drift tube.
