By Rajni A. Sethi, Igor J. Barani, David A. Larson, Mack Roach III
This instruction manual concisely summarizes cutting-edge information regarding stereotactic radiosurgery (SRS) and stereotactic physique radiotherapy (SBRT), together with the historical past and improvement of those modalities, the biologic reason for those applied sciences, ordinary practices, and said effects. built as a spouse to Handbook of Evidence-Based Radiotherapy, moment variation, edited by means of Eric Hansen and Mack Roach, III, it really is prepared through disorder website and provides remedy strategies and instructed imaging; security and caliber coverage; toxicities and administration; prompt follow-up; and aiding proof. Inclusion of evidence-based guidance is meant to assist tell judgements concerning the appropriateness of SRS and SBRT and consultant therapy and assessment. Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic physique Radiotherapy will be simply referenced within the health center and is a necessary consultant for oncology practitioners.
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Extra resources for Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy
Example text
Peri-orbital edema resolving with head elevation and warm compress. <1 % Risk of superficial skin infection. Acute (1 week to 6 months): Alopecia and skin changes following treatment of superficial lesions. Mild fatigue. Transient worsening of neurologic symptoms due to edema potentially requiring steroids. Late (>6 months): Radiation necrosis: Overall five-percent rate of symptomatic brain necrosis after SRS; typically resolves with steroids, but may require surgical intervention.
2007). Sphenopalatine Neuralgia (Sluder’s Neuralgia) Rare craniofacial pain syndrome with 2:1 female predominance associated with unilateral pain in the orbit, mouth, nose and posterior mastoid process as well as ipsilateral autonomic stimulation from vasomotor activity. R. Raleigh et al. Etiology unclear; perhaps related to pterygopalatine ganglion irritation from inflammation/infection of the sphenoid or posterior ethmoid sinuses. Radiosurgical data limited to case reports of sphenopalatine ganglion treatment (Pollock and Kondziolka 1997).
Chan N, Koritzinsky M, Zhao H, Bindra R, Glazer PM, et al. Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance. Cancer Res. 2008;68:605–14. The radioresponsiveness of human tumours and the initial slope of the cell survival curve. Radiother Oncol. 1984;2:317–23. Engaging the vascular component of the tumor response. Cancer Cell. 2005;8:89–91. Extending the linear-quadratic model for large fraction doses pertinent to stereotactic radiotherapy.
