By Amitava Dasgupta
Written in a guide type with particular equipment and pointers on taking out fake confident and fake adverse effects, this booklet is a realistic advisor to the designated mechanisms of such occurrences.
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Extra resources for Handbook of drug monitoring methods : therapeutics and drugs of abuse
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Since the 1960s, 5-fluorouracil has been used either alone or as part of a combination therapy with other drugs to treat various solid tumors and is also a standard therapy for colorectal cancer. Pharmacoki- 32 Dasgupta netic studies showed that clinical response as well as toxicity of 5-fluorouracil are related to AUC. Individual dosage adjustments based on pharmacokinetic monitoring lead to higher response rate of this drug as well as survival rates associated with tolerability. A limited sampling strategy using just two plasma concentrations can be used to predict AUC of 5-fluorouracil (165).