By Jan Egebjerg, Arne Schousboe, Povl Krogsgaard-Larsen
The ever present presence of glutamate and GABA receptors within the apprehensive approach makes those receptor structures pivotal to our realizing of neurotransmission. Cloning of the molecular elements of those receptor platforms has supplied insights to the selectivity of many medications and specific characterisation on the molecular point is rising. furthermore, non-stop improvement of novel and selective medicinal drugs has published exact info at the mechanism of receptor activation and rules. although, the speedy improvement of other features of glutamate and GABA receptor learn makes it more and more tough to set up a normal view of the sector. reports of the receptors are a multi-disciplinary job making use of many specialized concepts. This booklet conveys contemporary discoveries in a framework of the elemental strategies within the box of glutamate and GABA receptor learn. Glutamate and GABA Receptors and Transporters: constitution, functionality and Pharmacology is acceptable for postgraduate scholars learning ligand gated channels but additionally invaluable for commercial and educational study scientists in either the glutamate and GABA box. Universities supplying courses in neuroscience, molecular pharmacology or medicinal chemistry will locate this a helpful reference.
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Additional info for Glutamate and GABA Receptors and Transporters: Structure, Function and Pharmacology (The Taylor & Francis Series in Pharmaceutical Sciences)
Sample text
Q. and Gouaux, E. (1998) ‘Structure of a glutamate-receptor ligand-binding core in complex with kainate, Nature 395: 913–917. Ascher, P. and Nowak, L. (1988) ‘The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture’, J. Physiol. 399: 247–266. Bahring, R. L. (1998) ‘An analysis of philanthotoxin block for recombinant rat GluR6(Q) glutamate receptor channels’, J. Physiol. 509: 635–650. , Schousboe, A. F. (2000) ‘Control of GluR1 AMPA receptor function by cAMP-dependent protein kinase’, J.
Neurosci. 18: 720–730. F. J. (1999) ‘Lectin-induced inhibition of desensitization of the kainate receptor GluR6 depends on the activation state and can be mediated by a single native or ectopic N-linked carbohydrate side chain’, J. Neurosci. 19: 916–927. , Takahashi, T. G. (1994) ‘NMDA-receptor channel diversity in the developing cerebellum’, Nature 368: 335–339. Ionotropic glutamate receptors 33 Feldmeyer, D. G. (1994) ‘Elusive glutamate receptors’, Current Biology 4: 82–84. Feldmeyer, D. G. (1996) ‘Functional consequences of changes in NMDA receptor subunit expression during development’, J.
Rev. 51: 7–61. D. A. (1993) ‘GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses’, Neuron 10: 51–59. M. E. (1998) ‘The methylglutamate, SYM 2081, is a potent and highly selective agonist at kainate receptors’, J. Pharmacol. Exp. Ther. 285: 539–545. L. S. (1993) ‘Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C’, Proc. Natl. Acad. Sci. USA 90: 6731–6735.
