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Pharmaceutical Emulsions : A Drug Developer's Toolbag by Dipak Kumar Sarker

By Dipak Kumar Sarker

Pharmaceutical Emulsions: A Drug Developer's Toolbag covers the entire key elements of pharmaceutical emulsions, ranging from the elemental medical fundamentals, to the pharmaceutical varieties and the chemical assessments for its program. the writer makes use of his large event in either and educational event to supply a concise, scholar pleasant advisor to the basic basics of actual pharmacy.

Divided into 3 transparent sections,

The textual content starts off with part A - Consideration for Product: Medicinal Formulation which incorporates a ancient standpoint, rationalization of what's an emulsion, balance and instability, and manufacture.

Section B - Forms, Use and Application follows, with chapters on lotions and ointments, pastes and bases, colloids, transdermal, gels and implants.

The ultimate part, Tests: Chemistry to regulate the quality, efficacy and health for function of the product contains chapters on physic-chemical homes, sizing and microscopy, rheology, quality controls and eventually questions, calculations and dilemmas. through the textual content there are lots of figures, diagrams and tables to interact the reader.

This is a useful reference for all scholars of pharmaceutical sciences, pharmacy commercial pharmaceutical sciences, actual pharmacy and pharmaceutical kinds in addition to pros

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Active Pharmaceutical Ingredients: Development, by Stanley Nusim

By Stanley Nusim

Concentrating on the 3 most crucial elements that effectively deliver an API to market-process improvement, production, and governmental law and approval-this reference serves as a step by step advisor to the making plans and transparent knowing of the majority production of APIs. This consultant bargains present and well timed discussions of the method improvement cycle, layout engineering, the approval approach, qc and coverage, and validation, in addition to plant production actions together with fabrics administration, upkeep, and safeguard.

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Cyclin-Dependent Kinase (CDK) Inhibitors: Methods and by Mar Orzáez, Mónica Sancho Medina, Enrique Pérez-Payá

By Mar Orzáez, Mónica Sancho Medina, Enrique Pérez-Payá

This quantity incorporates a selection of proper details for drug discovery in cellphone cycle examine. Protocols to enhance screening assays or to spot novel CDK inhibitors are mentioned within the first a part of the publication. the second one a part of the ebook describes complex systems to guage task and mechanism of motion of recent and already pointed out CDK inhibitors. The 3rd a part of the booklet talks approximately protocols to guage metabolomics adjustments linked to inhibitor therapy. Drug supply thoughts desirous about nanoparticle improvement to supply substitute internalization platforms for expanding inhibitor efficacy also are defined. Written within the hugely profitable Methods in Molecular Biology series layout, chapters comprise introductions to their respective subject matters, lists of the required fabrics and reagents, step by step, easily reproducible laboratory protocols, and pointers on troubleshooting and heading off recognized pitfalls.

Authoritative and thorough, Cyclin-Dependent Kinase (CDK) Inhibitors: equipment and Protocols is an invaluable instrument for scientists attracted to this learn field.

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Taschenbuch der Arzneibehandlung: Angewandte Pharmakologie by G. Kuschinsky, Hasso Scholz, Ulrich Schwabe

By G. Kuschinsky, Hasso Scholz, Ulrich Schwabe

Haben Sie Fragen zu Arzneimittelauswahl und Therapieführung? Die thirteen. Auflage des Taschenbuchs der Arzneibehandlung bietet zuverlässige Informationen zur genauen Beurteilung der therapeutischen Wirkung der 1.500 meistverwendeten Arzneimittel. In 24 krankheitsbezogenen Kapiteln werden die Prinzipien der Arzneitherapie auf der foundation von Pathogenese und Symptomatik dargestellt (Teil I). Im zweiten, alphabetischen Teil werden die pharmakologischen Eigenschaften, Indikationen und Risiken von 1119 Arzneimitteln in Kurzmonographien beschrieben, Handelsnamen und Preise genannt. Jedes neue Medikament wird nach der Klassifikation von Fricke/Klaus hinsichtlich seiner therapeutischen Wirksamkeit bewertet. Darüber hinaus verweisen zahlreiche Internetadressen auf die aktuellen Leitlinien der Therapie der einschlägigen Fachgesellschaften und pharmakologischen Institutionen. Im Taschenbuch von Schwabe/Scholz finden Sie hilfreiche Informationen für eine intent und kostenbewusste Arzneitherapie.

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Lyophilized Biologics and Vaccines: Modality-Based by Dushyant Varshney, Manmohan Singh

By Dushyant Varshney, Manmohan Singh

This booklet offers a close account of the newest advancements, demanding situations and ideas to seamlessly boost and release a lyophilized biologics or vaccine product, according to assorted modalities, starting from antibodies (e.g., monoclonal, fused), complicated biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly consultant the reader via all an important facets, from biophysical and chemical balance concerns of proteins, analytical tools, advances in managed ice nucleation and quality-by-design methods, exchange drying expertise, to newest regulatory, packaging and know-how move concerns to increase a sturdy, secure and powerful healing protein, vaccine and biotechnology products.

Lyophilized Biologics and Vaccines: Modality-Based Approaches consists of 4 sections with a complete of 17 chapters. It serves as a connection with all severe exams and steps from early pre-formulation levels to product release:

  • Provides fresh knowing of heterogeneity of protein surroundings and choice of applicable buffer for stabilization of lyophilized formulations
  • Details the newest advancements in instrumental research and regulated ice nucleation know-how
  • Explains in-depth lyophilized (or dehydrated) formula innovations contemplating different modalities of biologics and vaccines, together with plasmid DNA and lipid-based therapeutics
  • Details an exhaustive replace on quality-by-design and technique analytical know-how ways, illustrated fantastically by way of case reports and FDA perspective
  • Provides the most recent targeted account of exchange drying applied sciences together with spray drying, bulk freeze-drying and crystallization, supported quite by way of case studies
  • Provides a step by step consultant via serious concerns in the course of technique scale-up, expertise move, packaging and drug supply gadget choice, for a winning lyophilization strategy validation, regulatory submission and product launch

Chapters are written via a number of world-renowned best specialists from academia, or regulatory enterprises, whose services disguise lyophilization of the varied modalities of biopharmaceuticals. Their contributions are in keeping with the exhaustive assessment of literature coupled with very good hands-on reports in laboratory or GMP setup, making this a superb consultant to all levels of lyophilized or dehydrated product development.

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The Handbook of Biomarkers by Kewal K. Jain

By Kewal K. Jain

Of the millions of biomarkers which are at present being came upon, fairly few are being confirmed for extra purposes, and the opportunity of a biomarker may be very tricky to guage. to help during this principal learn, Dr. Kewal ok. Jain’s Handbook of Biomarkers completely describes many differing types of biomarkers and their discovery utilizing quite a few "-omics" applied sciences, equivalent to proteomics and metabolomics, in addition to the heritage details wanted for the overview of biomarkers in addition to the fundamental systems for his or her validation and use in scientific trials. With biomarkers defined first in accordance with applied sciences after which in accordance with quite a few illnesses, this specific ebook gains the foremost correlations among ailments and classifications of biomarkers, which gives the reader with a consultant to tackle present and destiny biomarkers.

Comprehensive and state-of-the-art, The guide of Biomarkers serves as a necessary advisor to furthering our figuring out of biomarkers, which, by means of facilitating the combo of therapeutics with diagnostics, promise to play a tremendous position within the improvement of custom-made medication, probably the most very important rising tendencies in healthcare today.

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Toxicological profiles - Boron by Unknown

By Unknown

This ebook used to be digitized and reprinted from the collections of the college of California Libraries. It used to be made from electronic pictures created in the course of the libraries’ mass digitization efforts. The electronic photos have been wiped clean and ready for printing via computerized strategies. regardless of the cleansing technique, occasional flaws should still be current that have been a part of the unique paintings itself, or brought in the course of digitization. This publication and thousands of others are available on-line within the HathiTrust electronic Library at www.hathitrust.org.

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Toxicological profiles - Chlorophenols by Unknown

By Unknown

This booklet was once digitized and reprinted from the collections of the collage of California Libraries. It was once made out of electronic photographs created throughout the libraries’ mass digitization efforts. The electronic photos have been wiped clean and ready for printing via computerized procedures. regardless of the cleansing strategy, occasional flaws should be current that have been a part of the unique paintings itself, or brought in the course of digitization. This ebook and thousands of others are available on-line within the HathiTrust electronic Library at www.hathitrust.org.

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