By Shoib Ahmad Baba, Nasheeman Ashraf
This ebook is a made from years of study on saffron biology. It intends to provide a vast yet concise evaluate of many of the points of apocarotenoid biosynthesis in Crocus sativus, its legislation and pharmacology .
Crocus sativusL. of relatives Iridaceae is a crucial medicinal plant. The dried stigma of C. sativus flower is taken into account because the world's most costly spice. Saffron is the resources of special carotenoid derived molecules known as apocarotenoids which come with crocin, crocetin, picrocrocin and safranal. those molecules are synthesized within the tissue and developmental level particular demeanour. along with delivering color, aroma and flavour to the spice, those molecules have great medicinal value.
The booklet uncovers significant innovations of apocarotenoids biosynthesis and offers deeper and extra whole knowing approximately their biotechnological and pharmacological applications.
The ebook is split into 3 sections –
The first part presents a normal creation of C. sativus, its apocarotenoids, their biosynthesis, legislation and delivery. moment part offers information regarding the carotenoid cleavage dioxygenases (CCDs) that are the foremost gamers in apocarotenoid biosynthesis. The category of plant CCDs, their constitution, response mechanism, biotechnological software are completely mentioned. the ultimate part bargains with the key pharmacological homes of C. sativus apocarotenoids, starting from their function as anticancer to their software as neuroprotective molecules.
This is a one in every of its sort booklet on Crocus sativus. It may be worthy for the researchers operating on Crocus sativus, students and likewise practitioners interested in extraction and bio-synthesis of the worthwhile scientific components.
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Additional resources for Apocarotenoids of Crocus sativus L: From biosynthesis to pharmacology
1 Introduction Carotenoids are C40 isoprenoids and form one of the most diverse classes of natural compounds. They serve multitude of functions ranging from photosynthetic pigments to nutritional compounds and antioxidants. Carotenoids undergo a reaction involving incorporation of both oxygen atoms from molecular oxygen into their substrates across a double bond resulting in the production of two ketone- or aldehyde-containing cleavage products (Auldridge et al. 2006a, b). 1). They are widespread in plant kingdom and carry out vital physiological and developmental processes in plants.
Is an important medicinal plant and has been used widely in tropical and subtropical countries for treating a number of ailments. The use of saffron for medicinal purposes dates back to the Greek and Roman periods. It has been used to treat stomach disorders, flatulence, coughs, colic, insomnia, feminine disorder, and heart disease, as anodyne and tranquilizer, and for its emetic properties (Abdullaev et al. 2003). Saffron has been used in Chinese traditional medicine and is also mentioned in “Yi-Lin-Ji-Yao,” a traditional Chinese medical book composed during the Ming Dynasty (sixteenth century).
O. o. o. o. 4 weeks Agent C. sativus (petal) C. sativus (stigma) Reference Akhondzadeh et al. (2005) C. sativus (stigma) C. sativus (stigma) Akhondzadeh et al. (2010a) C. sativus (stigma) Donepezil Akhondzadeh et al. (2010b) C. sativus(stigma) C. sativus (stigma) Memantine Farokhnia et al. (2014) Crocin Talaei et al. 2 ml/kg) repaired the weakening activity of scopolamine (1 mg/kg) on memory in rats in the Morris water maze model. Besides it displayed no effect on intact memory. This was possibly because of its sedative effect through the BDZ site.